Jimmy Garoppolo passed for 349 yards and four touchdowns and Robbie Gould kicked a 30-yard field goal as time expired to give San Francisco a 48-46 victory over New Orleans. The Saints took their last lead on Drew Brees' fifth touchdown pass of the game with 53 seconds left. But Brees' pass on an attempted 2-point conversion fell incomplete. That left New Orleans' lead at one point. Garoppolo's clutch completion to tight end George Kittle for a 39-yard gain on fourth-and-2 from the San Francisco 33 helped the Niners set up Gould's winning kick.