(AP) — It was a night of upsets in men's college basketball as three of the nation's top four teams went down to defeat.

Katin Reinhardt nailed two free throws with 11.6 seconds remaining to send Marquette past top-ranked Villanova, 74-72. The Golden Eagles stormed back from a 17-point deficit and celebrated after Jalen Brunson missed a layup at the buzzer.

Reinhardt scored the game's final five points and finished with 19 as Marquette dropped the Wildcats to 19-2 overall and 7-2 in Big East play.

Esa Ahmad snapped out of his shooting slump with a career-high 27 points as 18th-ranked West Virginia handled No. 2 Kansas, 85-69. Ahmad had been held under 10 points for four straight games before scoring the Mountaineers' first eight points and finishing 10-for-17 from the field. He also started and finished a 12-1 run with baskets after WVU blew a double-digit lead in the second half for the third consecutive game.

Josh Jackson matched a season high with 22 points for the Jayhawks, who ended an 18-game winning streak with their fourth straight loss in Morgantown.

Fourth-ranked Kentucky had won seven in a row before Robert Hubbs III delivered 25 points for Tennessee in an 82-80 win against the visiting Wildcats. Admiral Schofield contributed 15 points to help the Vols beat Kentucky at Knoxville for the second straight year.

Malik Monk had 25 points for the Wildcats, who dropped to 17-3.

In other top-25 finals:

Virginia earned its 10th straight win over Notre Dame as London Perrantes scored 22 points to carry the 12th-ranked Cavaliers past the No. 14 Irish, 71-54 at South Bend. Isaiah Wilkins finished with 13 points and nine rebounds as the Cavs improved to 16-3.

No. 13 Louisville crushed Pittsburgh, 106-51, behind Donovan Mitchell's career-high 29 points. Anas Mahmoud added 14 points on 7 of 7 shooting as the Cardinals rebounded from a tough loss at Florida State and dealt the Panthers the second-worst loss in the program's 111-year history.

Wisconsin had an easy time with Penn State as Bronson Koenig hit for 20 points to lead the Badgers' 82-55 rout at Madison. Vitto Brown finished with 16 points, while Ethan Happ accounted for 14 and eight boards to help Wisconsin keep its share of the Big Ten lead at 6-1.

Caleb Swanigan contributed 25 points and 17 rebounds to lead No. 20 Purdue's 84-73 win at Michigan State. The Spartans dropped their third in a row despite Miles Bridges, who set the school's freshman scoring record with 33 points.

Maryland owns a share of the Big Ten lead at 6-1 after Melo Trimble scored 17 points to send the 22nd-rated Terrapins past Rutgers, 67-55. Freshman Kevin Huerter added 11 points as the Terps kept the Scarlet Knights winless in conference road games since joining the Big Ten in 2014.

No. 23 South Carolina hammered Auburn, 98-69 as Duane Notice tied career highs with six 3-pointers and 29 points. Sindarius Thornwell finished with 22 points and five 3-pointers to help the Gamecocks improve to 6-1 in the SEC.