Richard Sherman set up the only touchdown with another key defensive play in this heated rivalry, then made a second interception with the 49ers driving late, and the Seattle Seahawks ended a five-game losing streak on San Francisco's home field with a 19-3 win Thursday night.

Steven Hauschka kicked four field goals and the Seahawks' stout defense held Colin Kaepernick and Michael Crabtree in check as Seattle (8-4) overcame 14 penalties for 105 yards, including an offensive pass interference that negated a touchdown.

Russell Wilson passed for 236 yards and thoroughly outplayed Kaepernick, who had one of his worst performances for the 49ers (7-5).

After his second pick, Sherman looked at those fans still remaining in half-empty stadium on a Thanksgiving night and gave them the hush sign with his pointer finger to his mouth, then waved goodbye. The Seahawks won by the identical score they beat first-place Arizona five days earlier.

Kaepernick was just 16 for 29 for 121 yards.

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