UNDATED (AP) — You can cross UCLA off the list of unbeaten teams in Division I men's basketball.

Dillon Brooks nailed a 3-pointer with 0.8 seconds left to send No. 21 Oregon to an 89-87 win over the second-ranked Bruins. Brooks grabbed a missed free throw with 8.9 seconds left and dribbled to the right wing before scoring the last of his 23 points. Brooks also had nine rebounds for the 12-2 Ducks, while teammate Payton Pritchard finished with 15 points and nine assists in their 10th straight win.

UCLA fell to 13-1 despite Thomas Welch's 20 points and 10 boards.

Meanwhile, top-ranked Villanova has opened its Big East schedule by pulling out its 19th straight victory since last season's NCAA tournament.

Josh Hart scored 25 points and Jalen Brunson added 13 as the Wildcats got past DePaul, 68-65. Villanova saw a 51-39 lead become a 53-51 deficit before Hart dropped in 10 points over the final 3:06, including a game-clinching 3-pointer with 9.5 seconds left.

The Wildcats will carry a 13-0 record into Saturday's game at No. 10 Creighton.

The Bluejays tuned up for their meeting with Villanova by improving to 13-0 with an 89-75 triumph over Seton Hall. Maurice Watson had 21 points and 10 assists for Creighton, which is off to its best start since the 1942-43 team opened 16-0. Khyri Thomas and Justin Patton had 17 points apiece in the win.

In other top-25 finals:

— Devon Hall scored 10 points and Kyle Guy nailed a big jumper with 2:02 to play as 12th-ranked Virginia knocked off No. 6 Louisville, 61-53. The Cavaliers squandered most of a 21-point, second-half deficit before improving to 11-1 in the ACC opener for both schools.

— Justin Jackson scored 28 points and ninth-ranked North Carolina improved to 12-2 by pounding Monmouth, 102-74. Kennedy Meeks added 17 points and 12 rebounds, while Isaiah Hicks finished with 15 points.

— No. 15 Purdue won its Big Ten opener as freshman Carsen Edward scored 19 points and Dakota Mathias had 17 in an 89-67 drubbing of Iowa. Isaac Haas contributed 15 points to the Boilermakers' seventh straight win.

— Nebraska pulled off an 87-83 win over No. 16 Indiana behind Glynn Watson Jr.'s 26 points and Tai Webster's 21. The Hoosiers blew a 42-35 lead and ended their 26-game home winning streak.

— No. 17 Xavier thumped Providence, 82-56 as Trevon Bluiett scored 22 points and grabbed nine rebounds. Edmond Sumner added 13 points and seven rebounds for the 11-2 Musketeers, who led by as many as 30 in their Big East opener.

— Dwayne Bacon and Xavier Rathan-Mayes scored 23 points apiece as 20th-ranked Florida State beat Wake Forest, 88-72 in the ACC opener for both teams. Jonathan Isaac added 13 points for the 12-1 Seminoles, who have won nine straight for the first time in 13 years and are off to their best start since going 16-1 in 1988-89.

— Gary Clark's 11-point output included a pair of free throws with 14.9 seconds left to secure No. 23 Cincinnati's win at Temple, 56-50.

— V.J. Beachem scored 18 points and Bonzie Colson chipped in 10 points and eight boards in No. 24 Notre Dame's 63-55 triumph over Saint Peter's.

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